Natural, broad spectrum and water soluble preservative system

INCI name

Aqua, p-Anisic Acid, Polyglycerin-10, Polylysine, Coco-Glucoside


EPSAN® Plus is a new versatile and 100% plant-derived preservative system derived from p-anisic acid and polylysine that has an antimicrobial effect against yeasts, fungi, gram + and – bacteria, making it suitable for applications in the cosmetic industry and oral care.
This synergistic blend binds to polysaccharides (murein or bacterial mucopeptide) present in the cell walls of bacteria and denatures them, causing damage and inducing the micro-organisms to autolysis.
EPSAN® Plus is effective in a pH range comprised between 4.5 – 7.5, it is almost odourless and does not affect viscosity of the formula. Moreover, it has high thermal stability which makes it suitable to be treated with raw materials for sterilization or dispersed before emulsification. 
  • 100% plant-derived and palm-free
  • Claims “preservative-free” as its components are not classified as preservatives
  • p-Anisic Acid is found naturally in anise and has antiseptic or germ-killing properties
  • Polylysine is produced by bacterial fermentation, blocking the protein complex responsible of cellular proliferation
  • High thermal stability
  • Easy to use and effective in a pH range 4.5 – 7.5
  • Almost odourless and clearly soluble in water at all concentrations


Functional vegetal derivatives


   Appearance Clear liquid
   Colour Brown
   Odour Characteristic
   pH 5.5 – 7.5
   Dry residue (105°C) 65 – 67 %
  Specific gravity (25 °C) 1.17 ÷ 1.21



Skincare, Haircare, Personal care, Oral care.

It is advisable to not use substances obtained through a fermentation process in formulas containing EPSAN® Plus as preservative system (e.g. Xanthan Gum), because Polylysine binds to polysaccharides and denatures them.


Skin care (emulsions): 1.0-1.2%.
Hair care (emulsions): 1.0%.
Lotions: 0.8-1.0%.
Organic products: 1.2%.
Detergents: 0.8-1.0%



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