in & out DETOX®

Moisturizing, purifying plant-derived anti-pollution complex

moisturizing – purifying


INCI name

Polyglycerin-6, Propanediol, Solanum Melongena (Eggplant) Fruit Extract, Bioflavonoids, Brassica Oleracea Italica (Broccoli) Extract


in & out DETOX® is a 100% plant-derived anti-pollution and antioxidant complex with detoxifying and protecting effects on the tissue structure. It plays both an inner and outer protective role against stressors.
On one hand in & out DETOX® acts from inside and stimulates metabolic enzymes to get rid of toxins and reagents resulting from skin metabolic activity. On the other hand, it helps the skin fight against the outer stressors such as pollutants, UV radiations, free radicals and chemicals.
in & out DETOX® contributes also to the overall cleanliness of the skin: it inhibits sebum production and the proliferation of sebocytes, the cells that form the sebaceous gland. 
  • 100% plant-derived and palm-free.
  • It protects and defends the skin from pollutant substances and environmental stress factors. It activates the enzymes that oversee the detoxification process.
  • Improves pore cleanliness and balance sebum production.
  • Soluble in warm water, ethanol, glycerine and propylene glycol.



Synergistic blend of vegetal active compounds delivered in polyglycerol medium.

   Appearance Liquid
   Colour Light yellow
   Odour Characteristic
   pH 5.0 – 7.0
   Dry residue (105°C) 48- 52%
   Specific Gravity (25°C) 1.13 – 1.17


In-vivo tests show efficacy against free-radicals, provides significant antioxidant activity, TEWL reduction, skin moisture and pore cleanliness.

  • The skin hydration increases statistically significantly both in the first and in the fourth hour attesting around an average increase of 8%.

    Skin desquamation decreased by 37% after one hour.

    The sebometry was reduced by 22% in the first hour and 16% in the fourth hour.

    Discover more >> Moisturizing (short term) and Purifying activity

  • Skin hydration increases statistically significantly by 12% after 7 days of daily use.

    The lenitive efficacy of the product has been confirmed by a statistically significant reduction of 6% TEWL and the erythema of the 7% after 4 hours from the application of the product on a patch of skin irritation caused by SDS in cutaneous occlusion for 4 hours

    Discover more >> Moisturizing (long term) and Lenitive activity

  • In & out DETOX® significantly increased Superoxide dismutase expression, compared to untreated cells, after 6 hours of contact at the tested concentrations of 0.5%, 0.25% and 0.125% and, after 24 hours of contact, at the tested concentrations of 0.25% and 0.125%. In addition, a significant increase in catalase expression was observed at the concentration of 0.25% after 24 hours of contact.

    Discover more >> Antioxidant activity
  • IN & OUT DETOX is “non irritant”

    Discover more
    >> NRU

Ideal both for day & night emulsions as well as cleansing milks and transparent toners/micellar waters.
Ideal to be incorporated in non-toxic, completely biodegradable and safe O/W and W/O emulsions as well as transparent water-based applications.

% OF USE: 2.0%



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