Actives

HYDRO-B18®

Water-soluble form of 18-beta-glycyrrhetinic acid 

anti-inflammatory – antioxidant – soothing

 

INCI name

Aqua, Polyglyceryl-6 Caprylate, Glycyrrhetinic Acid, Proline

 

HYDRO-B18® is a cutting-edge water-soluble form of natural 18-ß-glycyrrhetinic acid which – in its original form – has poor bioavailability and very low water solubility. 18-ß-glycyrrhetinic acid is regarded as one of the most effective functional ingredients in nature with marked anti-inflammatory and soothing activity. It finds extensive use in the pharmaceutical sector and is often used in its derived salified version.
HYDRO-B18® contains 10% of free and intact 18-ß-glycyrrhetinic acid delivered in a 100% plant-derived medium. 
  • Transparent soluble in demineralized water at pH 7-9. The presence of surfactant allows widening its transparent solubility in a wider pH range.
  • 100% plant-derived and palm-free.
  • CORTISONE-LIKE INGREDIENT: cortisone-like ingredients such as glycyrrhetinic acid, relieves skin irritations without the typical side effects of corticosteroids. It can be applied daily as part of a preventive skincare regime for sensitive skin and especially in skincare products for infants who have not yet developed a protective hydro-lipid film or acid mantle.
  • ANTI-ITCHING ACTION Glycyrrhetinic acid reduces the rise of the itching. In particular, it has been shown the role of glycyrrhetinic acid in reducing chronic pruritus by reducing the level of leukotrienes produced.
  • ANTI-MELANOGENIC ACTION In vitro studies on cell lines has shown that treatment with glycyrrhizin and its aglycone, glycyrrhetinic acid — both before and during sun exposure — prevents oxidative damage.

 

 

ORIGIN

Natural 18-ß-glycyrrhetinic delivered in polyglycerol medium.

   Appearance Clear liquid
   Colour Yellow to light amber
   Odour Characteristic
   pH 7.5 – 9.5
   Dry residue (105°C) 55 ÷ 57 %
   Specific Gravity (25°C) 1.13 ÷ 1.15
   Solubility
Transparent soluble in demineralized water at pH 7-9. The presence of surfactant allows to widen its transparent solubility in a wider pH range.

TEST

  • In-vivo tests demonstrate soothing activity: 

    o – 16% TEWL after 2 applications of a cream containing 1% HYDRO-B18® on SDS-induced erythema
    o – 21% erythema index after 3 applications of a cream containing 1% HYDRO-B18® on SDS-induced erythema
    o In-vivo comparative tests show that HYDRO-B18® is more effective in treating erythema than standard Bisabolol and Ammonium Glycyrrhizate.

    Discover more >> Soothing activity

    Watch Video >> Soothing efficacy – HYDRO-B18

 

Skincare: transparent gels and emulsions for sensistive and irritated skins.
Sun care: after-sun transparent gels and emulsions

% OF USE: 1.0%

HYDRO B18® 

soothing efficacy

 

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