Actives extractives

PEARfect Tone®

Biomimetic UV light protection for skin brightening & tone evening

UV Light Protection – Skin Brightening – Tone Evening

INCI name

Glycerin, Pyrus Communis (Pear) Fruit Extract

 

 
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UV RADIATION DAMAGES

UV exposure accelerates skin aging, particularly in areas most exposed. This process, known as photoaging, results from prolonged radiation, primarily from the sun but also from artificial sources like tanning beds and sun lamps.

UVA, UVB, and UVC rays all contribute to photoageing, affecting all skin types. Common signs include hyperpigmentation, uneven texture, loss of elasticity, wrinkles, and redness, often due to melanin production triggered by melanogenesis and tyrosinase activation (Lipeng Wu et al., 2022).

Treatments like laser therapy, chemical peels, topical medications, and cryotherapy can help manage photodamage, even if they can’t fully erase it. But what if photoaging could be prevented?

PEAR STRATEGIES TO FIGHT UV RADIATIONS DAMAGES

Plants have developed a complex defense system to fight the harmful effects of UV radiation. When exposed, they produce protective molecules like flavonoids and other phenolic compounds that act as UV-absorbing sunscreens.

Pears accumulate flavonoids in their skin to block UV rays while their waxy cuticle reflects sunlight. Inside, they generate antioxidants that combat oxidative stress and defend against microbes, keeping the fruit healthy.

This blend of biochemical, structural, and molecular strategies effectively mitigate the impact of UV radiation, ensuring both survival and development.

Following a biomimetic approach and imitating pear’s defense system, we have developed PEARfect Tone®, a skin-brightening ingredient for UV protection.

THE SCIENCE BEHIND

PEARfect Tone® is formulated with Pyrus communis fruit extract derived from the Xuehua pear, naturally rich in flavonoid and polyphenols.

Through ultrasound-assisted extraction and tangential flow filtration, PEARfect Tone® is enriched with dihydromyricetin, UV absorber and tyrosinase inhibitor, along with arbutin, renowned for its skin-lightening effect against hyperpigmentation.

Its efficacy has been evaluated using a reconstructed human epidermis model comprising keratinocytes and melanocytes, which mimics highly differentiated human skin. The model has been exposed to UVA/UVB radiation for three days and treated with different concentrations of PEARfect Tone® to assess its protective and restorative properties.

HYPERPIGMENTATION INHIBITION

PEARfect Tone®, in human epidermis, significantly (p<0.05) reduces melanin production after UV exposure in a dose-dependent manner (Graph 1) and its activity is driven by the tyrosinase inhibition whom enzymatic activity, responsible of melanin synthesis, has been inhibited after 1 hour treatment at any concentrations tested (graph 2). Pictures of melanin production in human epidermidis (represented by brown color intensity) after UV exposure and PEARfect Tone® treatment are shown for each samples. The browner the epitelium becomes, the more melanin and radiation-induced damage increase. 

UV RADIATION IMPACT ON SKIN

  1. Accelerates skin aging of the most exposed areas affecting all skin types.
  2. Leads to hyperpigmentation, texture changes, loss of elasticity, wrinkles, and redness by stimulating melanin production.
  3. Treatments can reduce signs of photodamage without fully erasing them.

PYRUS COMMUNIS STRATEGIES

  1. Has evolved complex defenses producing protective molecules that act as natural sunscreens.
  2. Accumulates flavonoids in the skin to block UV rays and the waxy cuticle reflects sunlight.
  3. Combines biochemical, structural, and molecular strategies to protect from UV damage, supporting both survival and growth.

Pearfect tone®: A BIOMIMETIC SOLUTION

  1. Rich in dihydromyricetin, a UV absorbing flavonoid, and arbutin, helps lighten skin and reduce hyperpigmentation.
  2. Reduces melanin production in human epidermis after UV exposure.
  3. Reduces tyrosinase enzymatic activity responsible of melanin production.

Hair and scalp protection from UV radiations

Flavonoids are powerful antioxidants also for hair.

They have been shown to play a protective role in maintaining hair health by protecting it from UV-induced damage (Cižmárová B. et al., 2023; Bassino E. et al., 2020).

Flavonoids can reach the hair cortex, inhibit the formation of hair-derived radicals upon irradiation, and protect internal hair structures from oxidation thereby preserving the structural integrity of hair and preventing premature degradation (Dario M.F. et al., 2020).

  • UV Protection: PEARfect Tone® contains dihydromyricetin, a UV-absorbing flavonoid, and arbutin, providing natural protection against UV-induced damage and reducing hyperpigmentation.
  • Hyperpigmentation Inhibition: Effectively reduces melanin production in human epidermis models exposed to UV radiation by inhibiting tyrosinase enzymatic activity.
  • Biomimetic Approach: Inspired by Pyrus communis’ natural UV defense mechanisms, it replicates the pear’s strategy of combining antioxidants and protective molecules to shield the skin.
  • Eco-Friendly Profile: PEARfect Tone® is biodegradable, non-irritating, and safe for aquatic ecosystems, aligning with sustainability principles

ORIGIN

Plant extraction

 
   Appearance Clear Liquid
   Colour Light yellow
   Odour Characteristic
   pH 3.5 – 6.5
   Dry residue (105°C) >95%
   Specific Gravity (25°C) 1.2 – 1.3

Ideal for emulsions or transparent water-based formulations

% OF USE: 2.0 – 5.0%

 

 

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