actives extractives

multi FEEL®

Multi-target phyto complex — instant soothing & lasting comfort

soothing – antiredness – moisturizing

INCI name

Polyglycerin-6, Aqua, Propanediol, Centella Asiatica Leaf Extract, Scutellaria Baicalensis Root Extract, Hylocereus Undatus Fruit Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Berberis Vulgaris Root Extract, Rosmarinus Officinalis Leaf Extract

 

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MULTI FEEL® is a multi-target phyto complex for reactive skin. It addresses the three coexisting drivers of sensitivity – micro-inflammation, oxidative stress and barrier fragility – to deliver instant soothing and a rapid antioxidant shield after daily stressors (UV, surfactants, friction).

With continued use, MULTI FEEL® supports barrier recovery and hydration, helping the skin stay comfortable over time. It is easy to formulate in the water phase and performs best around skin-like pH.

COMPOSITION

  • Centella Asiatica Leaf Extract: Triterpenes support filaggrin & collagen III, reinforcing the barrier and aiding hydration recovery.

  • Scutellaria Baicalensis Root Extract:  Baicalin activates Nrf2 → HO-1, boosting endogenous antioxidant defenses.

  • Hylocereus Undatus Fruit Extract: Source of betacyanins; antioxidant support and balanced skin microbiome.

  • Camellia Sinensis Leaf Extract: EGCG provides rapid ROS scavenging, helpful under UV-induced stress.

  • Glycyrrhiza Glabra Root Extract: Glabridin helps down-modulate IKK/NF-κB, supporting reduction of IL-8/TNF-α.

  • Berberis Vulgaris Root Extract: Berberine helps inhibit IKK within the NF-κB cascade for anti-inflammatory action.

  • Rosmarinus Officinalis Leaf Extract: Phenolics (carnosic/rosmarinic acids) trap lipid peroxides and help protect/rebuild the lipid “mortar”.

efficacy tests

ANTI-INFLAMMATORY ACTION

Primary human keratinocytes are challenged with 200 ng/mL LPS to mimic a microbial insult, thereby activating the IKK/NF-κB pathway and sharply increasing IL-8 and TNF-α secretion.

Adding multi FEEL® at 1% and 1.5% reduces both cytokines (p < 0.01), bringing their levels closer to physiological values and confirming its potent anti-inflammatory action.

ANTIOXIDANT EFFICACY

Primary human keratinocytes are irradiated with UVA (5 J/cm²) to mimic photo-oxidative stress and trigger a rise in intracellular ROS.
 
Applying multi FEEL® at 0.5% or 1.5% cuts ROS levels by 28 and 21% respectively within 2 minutes, and the reduction persists at 10 minutes, confirming a fast and durable antioxidant effect.

SKIN BARRIER RECOVERY

IRRITATIVE HAND DERMATITIS: 15-DAY CLINICAL STUDY

Volunteers with irritative hand dermatitis — a condition with impaired hydration and barrier function (low corneometric values, high TEWL/erythema) — apply 2% multi FEEL® cream twice daily.
 
Corneometric values show a progressive recovery of hydration, bringing skin back within ranges typical of non-dehydrated conditions. In parallel, transepidermal water loss (TEWL) and erythema values decrease significantly (p < 0.05), indicating restoration of barrier function and visible soothing of reactive skin.

INSTANT SOOTHING – SDS-INDUCED ERYTHEMA

1% SDS patch is applied on volunteers forearm to induce irritant erythema.

A single topical dose of multi FEEL® cream reduces the clinical score to 1 at 1% and to 0 at 2–3%, confirming its strong soothing power and its ability to support the skin tolerability of formulations containing sulfate anionic surfactants (e.g., SLS, SLES), making it suitable for sensitive skin by helping to reduce signs of redness.

  • Plant-based, multi-target complex for reactive and easily irritated skin

  • Instant soothing with a rapid antioxidant shield after daily stressors

  • Progressive barrier support and comfort with continued use

  • Clinically tested on irritative skin (leave-on)

  • It proves to be effective against dermatitis at a concentration of 2%. It can also be used in skincare and haircare products at 1% in order to mitigate the aggressiveness of finished products
 

ORIGIN

Synergistic blend of vegetal active compounds delivered in polyglycerol medium.

   Appearance Liquid
   Colour Yellow
   Odour Characteristic
   pH 4.5 – 6.5
   Dry residue (105°C) 55 ÷ 65 %
   Specific Gravity (25°C)
1.165 – 1.185 

Designed for sensitive and reactive skin across multiple formats. Water-phase friendly and compatible with O/W and W/O emulsions, gels and wipes. Delivers instant soothing with a rapid antioxidant shield and supports barrier comfort over time.

Suitable for calming irritated and atopy-prone skin in O/W and W/O emulsions.

% OF USE:
1.0 – 3.0 %

 

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