Results – Efficacy in dermatitis treament – MULTI FEEL
All 20 subjects completed the study. The demographic characteristics of the sample are shown in table 1. All non-invasive tests were carried out by the same experimenter, between 10 and 14, at an average ambient temperature of 22 ° C and an average relative humidity of 57%.
| Characteristic | Frequency |
| n | 20 |
| drop-out | 0 |
| Male | 8 (40%) |
| Female | 12 (60%) |
| White | 20 (100%) |
| Black | 0 |
| Latino | 0 |
| Asian | 0 |
| Age (range) | 21 – 51 |
| Age (mean and SD) | 32,35 ± 7,04 |
Evaluation of cutaneous hydration. Skin hydration values increase statistically significantly in the Long Term Test (Table 2).
| MULTI FEEL® | t0 | t1h | t7d | t15g |
| Corneometric measurement | 36,61 ± 6,88 | 38,96 ± 5,83 | 40,29 ± 6,29 | 40,08 ± 6,25 |
|
Baseline change from t0 (mean and SD)
|
2,35 ± 7,92 | 3,68 ± 7,78 | 3,47 ± 6,56 | |
|
Percentage change from t0 (mean)
|
9,73 % | 12,8 % | 11,8 % | |
| p-value | 0,2005 | 0,048 | 0,0287 |
TEWL Evaluation
Both formulations determined a decrease in TEWL after 15 days of daily use (table 3).
| MULTI FEEL® | t0 | t1h | t7d | t15g |
| TEWL measurement | 13,82 ± 1,01 | 13,26 ± 1,67 | 12,91 ± 1,49 | 12,30 ± 1,80 |
|
Baseline change from t0 (mean and SD)
|
-0,5 ± 1,23 | -0,9 ± 1,06 | -0,9 ± 1,11 | |
|
Percentage change from t0 (mean)
|
-4,1 % | -6,6 % | -7,02 % | |
| p-value | 0,055 | 0,145 | 0,001 |
Colorimetry evaluation
The colorimetric values are reduced after 15 days of treatment (table 4).
| MULTI FEEL® | t0 | t1h | t7d | t15g |
| Mexameter E measurement | 299,9 ± 35,5 | 291,7 ± 34,8 | 279,0 ± 39,6 | 267,3 ± 41,0 |
|
Baseline change from t0 (mean and SD)
|
-8,2 ± 30,6 | -20, ± 30,7 | -24, ± 41,4 | |
|
Percentage change from t0 (mean)
|
-2,2 % | -6,6 % | -7,72 % | |
| p-value | 0,243 | 0,141 | 0,017 |