Efficacy test of MULTI FEEL® in dermatitis treatment

Erythematous dermatitis is a very common skin alteration in cosmetics and dermatology. It can be due to various causes that lead to acute, subacute or chronic dermal vasodilation. Among the most frequent cosmetological causes we can include climatic and environmental factors such as sunlight, abundant use of water or other irritating substances.

Irritative dermatitis is characterized by the appearance of erythema of various degrees that can be associated with a burning sensation and itching. The skin tends to dry out due to the loss of water in the horny layer and increased cell turnover which modifies the keratinocyte differentiation process and, consequently, the lipid content of the skin.

For the treatment of irritative dermatitis it is necessary to use topical products containing moisturizing principles, able to provide the lipids normally present in the epidermis so as to restore the skin’s hydrolipidic film and soothing principles with vasoconstrictive action; the effectiveness of these products is evaluated on the basis of their ability to reduce the degree of erythema and its symptoms.

In the medical literature there are numerous works that demonstrate the soothing action of numerous cosmetic principles (Katsarou 2000, Atrux-Tallau 2010, Szél 2015).

Evidence of efficacy can be evaluated in different ways (Colipa 1997) but testing on human volunteers is the preferred one. With the introduction of non-invasive instrumental measurement techniques that apply to humans, the properties of dermatological cosmetic products can be evaluated objectively, allowing the detection of subtle changes in skin morphology and function that would
otherwise not be detectable by sensory means.

These efficacy evaluations are essential to provide evidence-based support for manufacturers, dermo-cosmetic operators who need to give advice and the consumer.


Non-invasive techniques have been used in this research to assess the effects on hydration, TEWL and colorimetry of an active ingredient.