Conclusion – Efficacy test – antiwrinkles TOUCH®
Our studio was designed to evaluate the anti-wrinkle efficacy of an active ,of the company SOCRI – GREENGREDIENTS ® – called ANTIWRINKLES TOUCH ® – that was added to 4% in a cream .
In this experimentation we have used, a short term test and a long-term test, to evaluate the effectiveness of moisturizing, elasticizing and tolerability using a combination of non-invasive and clinical techniques.
In our study we wanted to test its effectiveness, in a short term test and long -term test, to evaluate their effectiveness anti-wrinkle, moisturizing, elasticizing and their tolerability. The short term test is important, in the efficacy studies, because it could have a high discriminating power as it is possible to achieve an improvement of the skin properties after a single application (Belo 2006).
On the other hand, long-term studies are important for evaluating the real effects, on the superficial layers of the skin, determined by the functional principles present in the product (Prall 1986, Berardesca 1997). In both types of tests, it is advisable to work with a sample of middle-aged volunteers in which the epidermis has more alterations. For these reasons, we have carried out the study on a middle-aged population.
In the present experimentation, we also used a combination of non-invasive and clinical techniques. Interpretation of the results revealed that there are significant increases in hydration and an improvement in some parameters of skin elasticity and roughness. Skin hydration increases in a statistically significant manner at all times studied and reaches a maximum value of 28% after 30 minutes from a single application and is around 13-16% in the long term test.
The skin elasticity improves in the short and long term tests . In fact, parameter R6 increases after 30 minutes and after 28 days of daily application of the product. The parameter R6 (Uv / Ue) indicates the viscoelasticity of the skin and its increase is correlated to an improvement of the epidermal hydration.
The R7 parameter increases reaching statistical significance after 30 days. The skin roughness showed an improvement in the SEsc and SEsm parameters. The SEsc parameter SOCRI ANTIWRINKLES TOUCH al 4% t0 t7d t30d Scaling Severity Score 2,5 ± 0,51 2,45 ± 0,51 2,4 ± 0,50 p-value 0,16 0,08
improves, decreasing its values, 7 and 28 days after daily application of the product.
The SEsc parameter indicates the degree of dryness of the stratum corneum the greater its value and the more the skin is hydrated as required for anti-aging products. The SEsm parameter improves, increasing its values, after 28 days. SEsm indicates the degree of skin smoothness: the tighter the skin and the higher its values.
The Scaling Severity Score showed a tendency to reduce the roughness in the long term test approaching the statistical significance after 28 days. To confirm these results and to make the data even more reliable, it would be necessary to increase the study sample and compare the product vs placebo or vs untreated area.